I loved the challenge I read about recently: to change, add or subtract a single letter to an existing word to make a whole new meaning.
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jocabulary: the language of laughter

windigestion: trouble at both ends

satnag: the sarcastic, panic-drven voice when you persist in making wrong turns

mygraine: 2 farmers arguing over their crops.

marsoupial: kangaroo broth

snidewalk: a really mean pavement

eunique: a sheep with character

t'issue: t'problem with a runny nose

hermitts: not your gloves

champaigne: fizzy wine headache

fictionary: made up words!

nocabulary: stuck for words